MW:50,000DabySDS-PAGE
ExtinctionCoefficient:1.35

Frozenin50mMTris-HCl,pH8.0,with200mMNaCland0.05%NaN3.

Storage:-20°C

BuyPurifiedNativeHumanImmunoglobulinG1(IgG1),FC,HumanMyelomaPlasma,FCFragment.
Price$230.00/mg.BulkQtyAvailable.

Crystallizablefragmentscomposedofthecarboxy-terminalhalvesofbothImmunoglobulinsHeavyChainslinkedtoeachotherbydisulfidebonds.Fcfragmentscontainthecarboxy-terminalpartsoftheheavychainconstantregionsthatareresponsIBLefortheeffectorfunctionsofanimmunoglobulin(Complementfixation,bindingtothecellmembraneviaFCReceptors,andplacentaltransport).IgG1FCwasreportedhasanovelroleasapotentialanti-inflammatorydrugfortreatmentofhumanautoimmunediseases.
Ref.AnthonyR,RavetchJ,etal.(2010),JClinImmunol.30Suppl1:S9-14

TheIgG1FCfragmentdoesnotbindantigen;however,itdoescontaintheclassicantigenicdeterminantsandBIOLOGicalactivitywithrespecttocytotrophicreactions,bindingofcomplementandcatabolicratecontrol.

Purity:>=95%bySDS-PAGE.

PreparedfromplasmashowntobenonreactiveforHBsAg,anti-HCV,anti-HBc,andnegativeforanti-HIV1&2byFDAapprovedtests.

AthensResearch&TechnologyproductsarelaboratoryreagentsandarenottobeadmiNISTeredtohumansorusedforanydrugpurpose.Forresearchorfurthermanufacturinguseonly.