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Athens Research & Technology/Immunoglobulin E (IgE), Human Plasma/16-16-090705/100 ug
MW:200,000
ExtinctionCoefficient:1.33
Ref:Ishiaka,K.1985.MethodsEnzymol.116,76.
Frozenin100mMTris,pH7.5,with200mMNaCland0.05%sodiumazide.
Storage:-20°C
BuyPurifiedNativeHumanImmunoglobulinE(IgE),HumanPlasma.
Price$265.00/100ug.BulkQtyAvailable.
IgEistheleastabundantimmunoglobulininplasma,foundataconcentrationoflessthat0.6micrograms/mlofnormalplasma.ElevatedIgElevelsarefoundinpatientsexperiencingsevereallergicreactionsandparasiticinfections.Inamyelomacondition,IgEisproducedbyasinglecloneofplasmacells.ThestructureofmyelomaIgE,however,isnormal,andtheimmunoglobulinpurifiedfromamyelomasourceisausefulproteinforstudyingimmunoglobulinbehavior.
Purity:>=95%bySDS-PAGE
ProductCitation:
Janssen,KrisPF,etal."Multiplexedproteindetectionusinganaffinityaptameramplificationassay." Analyticalandbioanalyticalchemistry 404,no.6-7(2012):2073-2081.
Schachermeyer,Samantha,etal."Aptamer-ProteinBindingDetectedbyAsymmetricFlowFieldFlowFractionation."JournalofChromatographyA (2013).
Abe,Takaaki,etal."AntibodyagainstimmunoglobulinEcontainedinbloodcomponentsascausativefactorforanaphylactictransfusionreactions." Transfusion (2014).
Kashiwakura,Jun-ichi,etal."MosthighlycytokinergicIgEshavepolyreactivitytoautoantigens." Allergy,asthma&immunologyresearch 4,no.6(2012):332-340.
PreparedfromplasmashowntobenonreactiveforHBsAg,anti-HCV,anti-HBc,andnegativeforanti-HIV1&2byFDAapprovedtests.
AthensResearch&TechnologyproductsarelaboratoryreagentsandarenottobeadmiNISTeredtohumansorusedforanydrugpurpose.Forresearchuseonly.
