
MW:225,000and125,000
Frozenin1xPBS
Storage:-70°Corlower
InterAlphaInhibitorProteins(IaIp)-includeInterAlphaTrypsinInhibitor(IaI)andPreAlphaInhibitor(Pal),withmolecularweightsof225kDaand125kDarespectively.Togethertheseproteinsarepresentinplasmaataconcentrationofapproximately50mg/100ml.Theinhibitoryactivityoftheproteinsisafunctionofbikunin,thecommonlightchainoftheIAIP.
Inacuteinflammation,thelalactsasanegativeacute-phaseprotein,whereasthePalactsasapositiveacute-phaseprotein.IaIparebeingconsideredasbioMarkersandbiotherapiesformetastaticdisease,septicshockandcomplementsystemdisorders.
Activity:Showsinhibitoryactivitywhentestedwithactive-sitetitratedporcinepancreatictrypsinusingNa-Benzoyl-L-Arginine-para-NitroanilideHydrochloride(L-BAPNA)assubstrate.
Purity:>=90%bySDSPAGE
Immunoblotting:Immunoreativewithanti-Bikunin
PreparedfromplasmashowntobenonreactiveforHBsAg,anti-HCV,anti-HBc,andnegativeforanti-HIV1&2byFDAapprovedtests.
AthensResearch&TechnologyproductsarelaboratoryreagentsproducedintheU.S.andarenottobeadmiNISTeredtohumansorusedforanydrugpurpose.
Forresearchuseorforuseinfurthermanufacturing.