
MW:28,000
ExtinctionCoefficient:1.22
Frozenin20mMNaAcetate,pH4.5,with1mMEDTAand100mMNaCl
Storage:-70°Corlower
BuyPurifiedNativeHumanCathepsinH(CatH),HumanLiver.
Price$132.00/25ug.BulkQtyAvailable.
AmorebasicproteinthanCathepsinBorL.Functionsasbothanaminopeptidaseandendopeptidase.CathepsinH,likecathepsinLandB,isinvolvedinthecatabolismofproteinsinthelysosomalsystem.
Ref:
Barrett,A.J.andKirschke,H.1981.MethodsEnzymol.80,535.
Barrett,A.J.1977.ProteinasesinMammalianCellsandTissues.(A.Barrett,ed.)4,209
Activity:greaterthan1unitpermgprotein.OneunitisdefinedastheamountofenzymethathydrolyzesoneumoleofL-arginine-beta-napthylamideperminuteat40oCusing75mMpotasiumphosphate,pH6.8,with1mMEDTAand3mMcysteineastheactivationbuffer.
ProductCitation:
DouglasLu,Weiya,LydianeFunkelstein,ThomasToneff,ThomasReinheckel,ChristophPeters,andVivianHook."CathepsinHfunctionsasanaminopeptidaseinsecretoryvesiclesforproductionofenkephalinandgalaninpeptideneurotransmitters." JournalofneuRochemistry 122,no.3(2012):512-522.
PreparedfromtissueshowntobenonreactiveforHbsAG,anti-HCV,anti-HBc,andnegativeforanti-HIV1&2byFDAapprovedtests.
AthensResearch&TechnologyproductsarelaboratoryreagentsandarenottobeadmiNISTeredtohumansorusedforanydrugpurpose.Forresearchuseonly.