

Oligo Synthesis : CEPs
Prices quoted are for single packs only. For multiples of the same product please request a quote. Some of Glen"sproductsarehazardousandmay be subject to additional shipping charges. Full product information is available onGlen Research"s website.
Asymmetric Doubler (Lev) Phosphoramidite
Asymmetric Doubler (Lev) Phosphoramidite
Glen Research
Catalogue No. | Description | Pack Size | Price | Qty |
|
---|---|---|---|---|---|
10-1981-02 | Asymmetric Doubler (Lev) Phosphoramidite | 0.25g | £200.00£190.00Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
10-1981-90 | Asymmetric Doubler (Lev) Phosphoramidite | 100 umoles | £84.00£79.80Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
Asymmetric Doubler (Lev) Phosphoramidite
Asymmetric Doubler (Lev) Phosphoramidite
Glen Research
Description: Asymmetric Doubler (Lev) Phosphoramidite
1-[5-(4,4’-dimethoxytrityloxy)pentylamido]-3-[5-levulinyloxypentylamido]-propyl- 2-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Diluent: Anhydrous Acetonitrile
Coupling: 6 minute coupling time recommended.
Deprotection: Levulinyl Deprotection: The levulinyl protecting group can be selectively removed without cleavage of the oligonucleotide from the CPG by treatment with 0.5M Hydrazine hydrate in 1:1 pyridine/acetic acid. [Note hydrazine hydrate is a violent poison that is both volatile and readily absorbed through skin] Fit the column with syringes and push the solution back and forth across the column. Let sit for 15 minutes at room temperature. Rinse the column with 1.5 mL of 1:1 pyridine/acetic acid (3x) and then 1.5 mL of ACN (3x). Dry CPG under a stream of argon and proceed with the synthesis of the branching sequence. If a non-branching control is desired, simply deprotect in ammonium hydroxide as required by the nucleobases.
Storage: Freezer storage, -10 to -30°C, dry
Stability in Solution: 1-2 Days
Click here for more information on Olignucleiotide Dendrimers
If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200