Oligo Synthesis : CEPs
Prices quoted are for single packs only. For multiples of the same product please request a quote. Some of Glen"sproductsarehazardousandmay be subject to additional shipping charges. Full product information is available onGlen Research"s website.
7-Deaza-8-aza-dG-CE Phosphoramidite (PPG )
7-Deaza-8-aza-dG-CE Phosphoramidite (PPG )
Glen Research
| Catalogue No. | Description | Pack Size | Price | Qty |
|
|---|---|---|---|---|---|
| 10-1073-02 | 7-Deaza-8-aza-dG-CE Phosphoramidite (PPG ) | 0.25g | £1,280.00£874.00Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
| 10-1073-90 | 7-Deaza-8-aza-dG-CE Phosphoramidite (PPG ) | 100µmoles | £440.00£300.20Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
| 10-1073-95 | 7-Deaza-8-aza-dG-CE Phosphoramidite (PPG ) | 50µmoles | £228.00£157.70Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
Related products
7-Deaza-8-aza-dG-CE Phosphoramidite (PPG )
7-Deaza-8-aza-dG-CE Phosphoramidite (PPG )
Glen Research
| 7-Deaza-8-aza-dG-CE Phosphoramidite (PPG ) |
Catalog Number: 10-1073-xx
Description: 7-Deaza-8-aza-dG-CE Phosphoramidite (PPG)
| 5"-Dimethoxytrityl-N-dimethylformamidine-8-aza-7-deaza-2"-deoxyGuanosine,3"-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | ||
| Formula: C43H53N8O7P | M.W.: 824.91 | F.W.: 329.20 |
Diluent: Anhydrous Acetonitrile |
| Coupling: No changes needed from standard method recommended by synthesizer manufacturer. |
| Deprotection: No changes needed from standard method recommended by synthesizer manufacturer. |
| Storage: Refrigerated storage, maximum of 2-8°C, dry |
| Stability in Solution: |
Please Note: This Product is for research purposes only, and may not be used for commercial, clinical, diagnostic or any other use. The Product is subject to proprietary rights of Epoch Biosciences, Inc. and is made and sold under license from Epoch Biosciences, Inc.There is no implied license for commercial use with respect to this Product and a license must be obtained directly from Epoch Biosciences, Inc. with respect to any proposed commercial use of this Product."Commercial use" includes but is not limited to the sale, lease, license or other transfer of the Product or any material derived or produced from it, the sale, lease, license or other grant of rights to use the Product or any material derived or produced from it, or the use of the Product to perform services for a fee for third parties (including contract research). Eclipse, Gig Harbor Green, Redmond Red and Yakima Yellow are trademarks of Epoch Biosciences, Inc. STRUCTURE/ACTIVITY RELATIONSHIPThe following products are used to investigate the effect on theactivity of an oligonucleotide when key structural elements are changed. The7-deaza purine monomers lack groups critical for hydrogen bonding.7-Deaza-8-aza-A and 7-deaza-8-aza-G (PPG) monomers are isomers of A and G andhave similar electron density. Their presence in oligos is slightly stabilizingrelative to A and G. Unlike G, PPG does not lead to aggregation and G-richoligos can be easily prepared and isolated. 5’-Fluorescein oligos with PPG atthe 5’-terminus are much less quenched than the equivalent G oligos. As a purineanalogue of Thymidine, 7-deaza-2’-deoxyXanthosine (7-deaza-dX) promises to haveinteresting effects on DNA structure of triplexes. 7-Deaza-dX also forms anon-standard base pair with a 2,4-diaminopyrimidine nucleoside analogue.Standard nucleobases have an unshared pair of electrons that project into theminor groove of duplex DNA. Enzymes that interact with DNA, polymerases, reversetranscriptases, restriction enzymes, etc., may use a hydrogen bond donatinggroup to contact the hydrogen bond acceptor in the minor groove.3-Deaza-2’-deoxyadenosine is very interesting in that it maintains the abilityfor regular Watson-Crick hydrogen bonding to T but is lacking the electron pairat the 3-position normally provided by N3. |
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7-Deaza-8-aza-dG-CE Phosphoramidite (PPG )
7-Deaza-8-aza-dG-CE Phosphoramidite (PPG )
Glen Research
MSDS
Glen Report 15.1: MORE AND still MORE NOVEL MINOR BASES
If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
7-Deaza-8-aza-dG-CE Phosphoramidite (PPG )
7-Deaza-8-aza-dG-CE Phosphoramidite (PPG )
Glen Research
DILUTION/COUPLING DATA
The table below shows pack size data and, for solutions, dilutions and approximate couplings based on normal priming procedures. Please link for more detailed usage information with the various synthesizers.
| ABI 392/394 | |||||||||
| Cat.No. | PackSize | Grams/Pack | 0.1M Dil.(mL) | LV40 | LV200 | 40nm | 0.2µm | 1µm | 10µm |
| Approximate Number of Additions | |||||||||
| 10-1073-02 | 0.25grams | .25grams | 3.03 | 87.67 | 52.6 | 32.88 | 23.91 | 17.53 | 4.38 |
| 10-1073-90 | 100µmoles | .082grams | 1 | 20 | 12 | 7.5 | 5.45 | 4 | 1 |
| 10-1073-95 | 50µmoles | .041grams | .5 | 3.33 | 2 | 1.25 | .91 | .67 | .17 |
| Expedite | |||||||||
| Cat.No. | PackSize | Grams/Pack | Dilution(mL) | Molarity | 50nm | 0.2µm | 1µm | 15µm | |
| Approximate Number of Additions | |||||||||
| 10-1073-02 | 0.25grams | .25grams | 4.52 | .07 | 84 | 52.5 | 38.18 | 5.25 | |
| 10-1073-90 | 100µmoles | .082grams | 1.5 | .07 | 23.6 | 14.75 | 10.73 | 1.48 | |
| 10-1073-95 | 50µmoles | .041grams | .75 | .07 | 8.6 | 5.38 | 3.91 | .54 | |
| Beckman | |||||||||
| Cat.No. | PackSize | Grams/Pack | Dilution(mL) | Molarity | 30nm | 200nm | 1000nm | ||
| Approximate Number of Additions | |||||||||
| 10-1073-02 | 0.25grams | .25grams | 4.52 | .07 | 85.6 | 53.5 | 38.91 | ||
| 10-1073-90 | 100µmoles | .082grams | 1.5 | .07 | 25.2 | 15.75 | 11.45 | ||
| 10-1073-95 | 50µmoles | .041grams | .75 | .07 | 10.2 | 6.38 | 4.64 | ||
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