Oligo Synthesis : CEPs
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5"-Amino-Modifier C6
5"-Amino-Modifier C6
Glen Research
| Catalogue No. | Description | Pack Size | Price | Qty |
|
|---|---|---|---|---|---|
| 10-1906-02 | 5"-Amino-Modifier C6 | 0.25g | £160.00£152.00Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
| 10-1906-90 | 5"-Amino-Modifier C6 | 100µmoles | £48.00£45.60Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
Related products
5"-Amino-Modifier C6
5"-Amino-Modifier C6
Glen Research
| 5"-Amino-Modifier C6 |
Catalog Number: 10-1906-xx
Description: 5"-Amino-Modifier C6
| 6-(4-Monomethoxytritylamino)hexyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite | ||
| Formula: C35H48N3O3P | M.W.: 589.76 | F.W.: 179.16 |
Diluent: Anhydrous AcetonitrileAdd fresh diluent to product vial to recommended concentration and swirl vial occasionally over several minutes until product is completely dissolved.(Some oils may require between 5 and 10 minutes.) Use care to maintain anhydrous conditions.In case of transfer to alternate vial type, ensure recipient vial has been pre-dried. For more information, see http://www.glenres.com/Technical/TB_ABITransfer.pdf. |
| Coupling: No changes needed from standard method recommended by synthesizer manufacturer. |
| Deprotection: Deprotect as required by nucleobases.WARNING:Drying down the oligo after cleavage and deprotection without addition of an non-volatile base (for example, TRIS) will lead to loss of the Trityl protecting group. Technical Bulletin |
| Storage: Freezer storage, -10 to -30°C, dry |
| Stability in Solution: 2-3 days |
TERMINUS MODIFIERS
Glen Research 5’-Modifiers are designed for use in DNA synthesizers tofunctionalize the 5’-terminus of the target oligonucleotide. The5’-Amino-Modifiers are available with a variety of chain lengths to fit exactlythe desired application.
The DMS(O)MT-protected amino group is easier to deprotect compared to theMMT-protected one. The sulfoxy derivative survives conditions of oligonucleotidesynthesis and can either be cleaved with standard deblock solution, or leftintact for HPLC purification. At the same time, the DMS(O)MT group is fullycompatible with cartridge purification. When detritylation on a cartridge iscarried out, the DMS(O)MT , which is more stable than MMT , does not reattachitself to an amine. We now offer 5’-DMS(O)MT-Amino-Modifier C6 utilizing thisnew trityl based protecting group.
5’-Amino-Modifier TEG, a hydrophilic triethylene glycol ethylaminederivative, is 12 atoms in length and fully soluble in aqueous media.
If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
5"-Amino-Modifier C6
5"-Amino-Modifier C6
Glen Research
MSDS
If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
5"-Amino-Modifier C6
5"-Amino-Modifier C6
Glen Research
Technical Notes
MicroNanoBeyond.pdf:
If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
5"-Amino-Modifier C6
5"-Amino-Modifier C6
Glen Research
DILUTION/COUPLING DATA
The table below shows pack size data and, for solutions, dilutions and approximate couplings based on normal priming procedures. .
| ABI 392/394 | |||||||||
| Cat.No. | PackSize | Grams/Pack | 0.1M Dil.(mL) | LV40 | LV200 | 40nm | 0.2µm | 1µm | 10µm |
| Approximate Number of Additions | |||||||||
| 10-1906-02 | 0.25grams | .25grams | 4.24 | 128 | 76.8 | 48 | 34.91 | 25.6 | 6.4 |
| 10-1906-90 | 100µmoles | .059grams | 1 | 20 | 12 | 7.5 | 5.45 | 4 | 1 |
| Expedite | |||||||||
| Cat.No. | PackSize | Grams/Pack | Dilution(mL) | Molarity | 50nm | 0.2µm | 1µm | 15µm | |
| Approximate Number of Additions | |||||||||
| 10-1906-02 | 0.25grams | .25grams | 6.33 | .07 | 120.2 | 75.13 | 54.64 | 7.51 | |
| 10-1906-90 | 100µmoles | .059grams | 1.5 | .07 | 23.6 | 14.75 | 10.73 | 1.48 | |
| Beckman | |||||||||
| Cat.No. | PackSize | Grams/Pack | Dilution(mL) | Molarity | 30nm | 200nm | 1000nm | ||
| Approximate Number of Additions | |||||||||
| 10-1906-02 | 0.25grams | .25grams | 6.33 | .07 | 121.8 | 76.13 | 55.36 | ||
| 10-1906-90 | 100µmoles | .059grams | 1.5 | .07 | 25.2 | 15.75 | 11.45 | ||
If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
