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商品详细Athens Research/Cambio - Excellence in Molecular Biology/10-1088-90
Athens Research/Cambio - Excellence in Molecular Biology/10-1088-90
Athens Research/Cambio - Excellence in Molecular Biology/10-1088-90
商品编号: 10-1088-90
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产品分类: 多肽合成
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商品介绍
Oligo Synthesis

Oligo Synthesis : CEPs

Prices quoted are for single packs only. For multiples of the same product please request a quote. Some of Glen"sproductsarehazardousandmay be subject to additional shipping charges. Full product information is available onGlen Research"s website.

  • Catalogue
  • Description
  • Protocols
  • Applications & Benefits

3-deaza-dA-CE Phosphoramidite

3-deaza-dA-CE Phosphoramidite

Glen Research

Catalogue No.DescriptionPack SizePriceQty
  • Change to:
  • €
10-1088-023-deaza-dA-CE Phosphoramidite0.25g£780.00£741.00Offer until : 31-Dec-2020Offer Code : GLEN55% off all Glen productsView OfferQuantityAdd to Order
10-1088-903-deaza-dA-CE Phosphoramidite100µmoles£284.00£269.80Offer until : 31-Dec-2020Offer Code : GLEN55% off all Glen productsView OfferQuantityAdd to Order
10-1088-953-deaza-dA-CE Phosphoramidite50µmoles£142.00£134.90Offer until : 31-Dec-2020Offer Code : GLEN55% off all Glen productsView OfferQuantityAdd to Order

3-deaza-dA-CE Phosphoramidite

3-deaza-dA-CE Phosphoramidite

Glen Research

3-deaza-dA-CE Phosphoramidite

Structure

Catalog Number: 10-1088-xx

Description: 3-deaza-dA-CE Phosphoramidite

5"-Dimethoxytrityl-N-benzoyl-3-deaza-2"-deoxyAdenosine,3"-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Formula: C48H53N6O7PM.W.: 856.95F.W.: 312.22

Diluent: Anhydrous Acetonitrile
Coupling: No changes needed from standard method recommended by synthesizer manufacturer.
Deprotection: No changes needed from standard method recommended by synthesizer manufacturer. Note: Not compatible with mild deprotection at room temperature.
Storage: Refrigerated storage, maximum of 2-8°C, dry
Stability in Solution: 2-3 days

STRUCTURE/ACTIVITY RELATIONSHIP

The following products are used to investigate the effect on theactivity of an oligonucleotide when key structural elements are changed. The7-deaza purine monomers lack groups critical for hydrogen bonding.7-Deaza-8-aza-A and 7-deaza-8-aza-G (PPG) monomers are isomers of A and G andhave similar electron density. Their presence in oligos is slightly stabilizingrelative to A and G. Unlike G, PPG does not lead to aggregation and G-richoligos can be easily prepared and isolated. 5’-Fluorescein oligos with PPG atthe 5’-terminus are much less quenched than the equivalent G oligos. As a purineanalogue of Thymidine, 7-deaza-2’-deoxyXanthosine (7-deaza-dX) promises to haveinteresting effects on DNA structure of triplexes. 7-Deaza-dX also forms anon-standard base pair with a 2,4-diaminopyrimidine nucleoside analogue.Standard nucleobases have an unshared pair of electrons that project into theminor groove of duplex DNA. Enzymes that interact with DNA, polymerases, reversetranscriptases, restriction enzymes, etc., may use a hydrogen bond donatinggroup to contact the hydrogen bond acceptor in the minor groove.3-Deaza-2’-deoxyadenosine is very interesting in that it maintains the abilityfor regular Watson-Crick hydrogen bonding to T but is lacking the electron pairat the 3-position normally provided by N3.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

3-deaza-dA-CE Phosphoramidite

3-deaza-dA-CE Phosphoramidite

Glen Research

MSDS

Glen Report 17.1

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

3-deaza-dA-CE Phosphoramidite

3-deaza-dA-CE Phosphoramidite

Glen Research

DILUTION/COUPLING DATA

The table below shows pack size data and, for solutions, dilutions and approximate couplings based on normal priming procedures.

ABI 392/394
Cat.No.PackSizeGrams/Pack0.1M Dil.(mL)LV40LV20040nm0.2µm1µm10µm
Approximate Number of Additions
10-1088-020.25grams.25grams2.928450.431.522.9116.84.2
10-1088-90100µmoles.086grams120127.55.4541
10-1088-9550µmoles.043grams.53.3321.25.91.67.17
Expedite
Cat.No.PackSizeGrams/PackDilution(mL)Molarity50nm0.2µm1µm15µm
Approximate Number of Additions
10-1088-020.25grams.25grams4.35.0780.650.3836.645.04
10-1088-90100µmoles.086grams1.5.0723.614.7510.731.48
10-1088-9550µmoles.043grams.75.078.65.383.91.54
Beckman
Cat.No.PackSizeGrams/PackDilution(mL)Molarity30nm200nm1000nm
Approximate Number of Additions
10-1088-020.25grams.25grams4.35.0782.251.3837.36
10-1088-90100µmoles.086grams1.5.0725.215.7511.45
10-1088-9550µmoles.043grams.75.0710.26.384.64

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

品牌介绍
Athens Research & Technology—供应多款蛋白、酶制品 Athens Research & Technology是成立于2010年的新兴生物高科技制品公司,该公司拥有BSL-2实验室及超过11000平方英尺的cGMP生产厂房,并且通过ISO 9001:2008认证。Athens公司致力于纯化分离高纯度,高活性的人类蛋白质及研发多克隆抗血清产品。提供包括高纯度及活性的丝氨酸蛋白酶,蛋白酶抑制剂,中性粒细胞酶,载脂蛋白,脂蛋白,血小板蛋白,转铁蛋白,免疫球蛋白等等。公司产品适用于炎症,冠状动脉疾病,自身免疫性疾病,癌症,阿尔茨海默氏病等众多研究领域,已被世界*制药公司及诊断试剂公司用于体外诊断试剂盒/免疫检测试剂盒、药物筛选、细胞培养液(包括干细胞)等产品研发。除了人类蛋白质,我们还从动物血清和组织中分离多种蛋白质及酶类。此外,Athens Research and Technology还提供特殊试剂/蛋白定制服务,以满足研究人员的不同需求。