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商品详细Athens Research/Cambio - Excellence in Molecular Biology/0.25g/10-3190-02
Athens Research/Cambio - Excellence in Molecular Biology/0.25g/10-3190-02
Athens Research/Cambio - Excellence in Molecular Biology/0.25g/10-3190-02
商品编号: 10-3190-02
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产地: 美国(厂家直采)
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产品分类: 多肽合成
公司分类: peptide
联系Q Q: 3392242852
电话号码: 4000-520-616
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商品介绍
Oligo Synthesis

Oligo Synthesis : CEPs

Prices quoted are for single packs only. For multiples of the same product please request a quote. Some of Glen"sproductsarehazardousandmay be subject to additional shipping charges. Full product information is available onGlen Research"s website.

  • Catalogue
  • Description
  • Protocols
  • Applications & Benefits

2"-OMe-5-Br-U-CE Phosphoramidite

2"-OMe-5-Br-U-CE Phosphoramidite

Glen Research

Catalogue No.DescriptionPack SizePriceQty
  • Change to:
  • €
10-3190-022"-OMe-5-Br-U-CE Phosphoramidite0.25g£692.00£513.00Offer until : 31-Mar-2021Offer Code : GLEN55% off all Glen productsView OfferQuantityAdd to Order
10-3190-902"-OMe-5-Br-U-CE Phosphoramidite100µmoles£248.00£182.40Offer until : 31-Mar-2021Offer Code : GLEN55% off all Glen productsView OfferQuantityAdd to Order

2"-OMe-5-Br-U-CE Phosphoramidite

2"-OMe-5-Br-U-CE Phosphoramidite

Glen Research

2"-OMe-5-Br-U-CE Phosphoramidite

Structure

Catalog Number: 10-3190-xx

Description: 2"-OMe-5-Br-U-CE Phosphoramidite

5"-Dimethoxytrityl-5-bromo-Uridine,2"-O-methyl,3"-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Formula: C40H48BrN4O9PM.W.: 839.72F.W.: 399.09

Diluent:Acetonitrile:THF (1:1)
Coupling: Dissolve in Acetonitrile:THF (1:1).A 6 minute coupling time is recommended.
Deprotection: Mild deprotection: Ammonium Hyrdoxide for 24 hours at room temperature.
Storage: Freezer storage, -10 to -30°C, dry
Stability in Solution: 2-3 days

minor 2’-Ome-rnaphosphoramidites

To aid in the evaluation of the structures of 2’-OMe-RNAcomplexes, we offer the CE phosphoramidites listed below. 2’-OMe-T is useful intriplex studies while the 2-aminopurine derivative may be tested in ribozymestudies. By supporting an additional hydrogen bond, 2,6-diaminopurine(2-amino-adenosine) binds more strongly with uridine than does adenosine.Oligonucleotides containing 2’-OMe-5-Me-C and 2’-OMe-I would be of interest toresearchers involved in triplex and antisense studies using 2’-OMe-RNA. The usesof 2’-OMe-5-bromo-U phosphoramidite range from crystallographic studies due tothe heavy atom to cross-linking because of its photolability.5-Fluoro-pyrimidine nucleosides have been useful as therapeutic agents and theireffect on the structure and activity of oligonucleotides may be examined usingthe 2’-OMe-RNA derivatives. The 2,4,6-trimethylphenyl (TMP) protected 2’-OMe-Uderivative is a convertible nucleoside and reaction with ammonia leads to the5-fluoro-dC analogue. 2’-OMe-3-deaza-5-aza-C (Reverse C) derivative has thepotential to mimic in oligonucleotides 5-azacytidine, a DNA methylase inhibitor.Its ability to bind as a C will likely be diminished.ABI-style vials aresupplied unless otherwise requested (see note box).

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

2"-OMe-5-Br-U-CE Phosphoramidite

2"-OMe-5-Br-U-CE Phosphoramidite

Glen Research

MSDS

Glen Report 11.2

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

2"-OMe-5-Br-U-CE Phosphoramidite

2"-OMe-5-Br-U-CE Phosphoramidite

Glen Research

DILUTION/COUPLING DATA

The table below shows pack size data and, for solutions, dilutions and approximate couplings based on normal priming procedures.

ABI 392/394
Cat.No.PackSizeGrams/Pack0.1M Dil.(mL)LV40LV20040nm0.2µm1µm10µm
Approximate Number of Additions
10-3190-020.25grams.25grams2.988651.632.2523.4517.24.3
10-3190-90100µmoles.084grams120127.55.4541
Expedite
Cat.No.PackSizeGrams/PackDilution(mL)Molarity50nm0.2µm1µm15µm
Approximate Number of Additions
10-3190-020.25grams.25grams4.44.0782.451.537.455.15
10-3190-90100µmoles.084grams1.5.0723.614.7510.731.48
Beckman
Cat.No.PackSizeGrams/PackDilution(mL)Molarity30nm200nm1000nm
Approximate Number of Additions
10-3190-020.25grams.25grams4.44.078452.538.18
10-3190-90100µmoles.084grams1.5.0725.215.7511.45

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

品牌介绍
Athens Research & Technology—供应多款蛋白、酶制品 Athens Research & Technology是成立于2010年的新兴生物高科技制品公司,该公司拥有BSL-2实验室及超过11000平方英尺的cGMP生产厂房,并且通过ISO 9001:2008认证。Athens公司致力于纯化分离高纯度,高活性的人类蛋白质及研发多克隆抗血清产品。提供包括高纯度及活性的丝氨酸蛋白酶,蛋白酶抑制剂,中性粒细胞酶,载脂蛋白,脂蛋白,血小板蛋白,转铁蛋白,免疫球蛋白等等。公司产品适用于炎症,冠状动脉疾病,自身免疫性疾病,癌症,阿尔茨海默氏病等众多研究领域,已被世界*制药公司及诊断试剂公司用于体外诊断试剂盒/免疫检测试剂盒、药物筛选、细胞培养液(包括干细胞)等产品研发。除了人类蛋白质,我们还从动物血清和组织中分离多种蛋白质及酶类。此外,Athens Research and Technology还提供特殊试剂/蛋白定制服务,以满足研究人员的不同需求。