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商品详细Athens Research/Cambio - Excellence in Molecular Biology/100µmoles/10-3124-90
Athens Research/Cambio - Excellence in Molecular Biology/100µmoles/10-3124-90
Athens Research/Cambio - Excellence in Molecular Biology/100µmoles/10-3124-90
商品编号: 10-3124-90
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产地: 美国(厂家直采)
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产品分类: 多肽合成
公司分类: peptide
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商品介绍
Oligo Synthesis

Oligo Synthesis : CEPs

Prices quoted are for single packs only. For multiples of the same product please request a quote. Some of Glen"sproductsarehazardousandmay be subject to additional shipping charges. Full product information is available onGlen Research"s website.

  • Catalogue
  • Description
  • Protocols
  • Applications & Benefits

2"-OMe-2,6-Diaminopurine-CE Phosphoramidite

2"-OMe-2,6-Diaminopurine-CE Phosphoramidite

Glen Research

Catalogue No.DescriptionPack SizePriceQty
  • Change to:
  • €
10-3124-022"-OMe-2,6-Diaminopurine-CE Phosphoramidite0.25g£800.00£741.00Offer until : 31-Mar-2021Offer Code : GLEN55% off all Glen productsView OfferQuantityAdd to Order
10-3124-902"-OMe-2,6-Diaminopurine-CE Phosphoramidite100µmoles£312.00£269.80Offer until : 31-Mar-2021Offer Code : GLEN55% off all Glen productsView OfferQuantityAdd to Order
10-3124-952"-OMe-2,6-Diaminopurine-CE Phosphoramidite50µmoles£164.00£134.90Offer until : 31-Mar-2021Offer Code : GLEN55% off all Glen productsView OfferQuantityAdd to Order

2"-OMe-2,6-Diaminopurine-CE Phosphoramidite

2"-OMe-2,6-Diaminopurine-CE Phosphoramidite

Glen Research

2"-OMe-2,6-Diaminopurine-CE Phosphoramidite

Structure

Catalog Number: 10-3124-xx

Description: 2"-OMe-2,6-Diaminopurine-CE Phosphoramidite

5"-Dimethoxytrityl-N2-isobutyryl-N6-dimethylaminomethylidene-2"-O-methyl-2,6-diaminopurineriboside,3"-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Formula: C48H62N9O8PM.W.: 924.05F.W.: 358.25

Diluent: Anhydrous Acetonitrile
Coupling: 6 minute coupling time
Deprotection: Complete deprotection takes 5 days at 55oC with ammonium hydroxide.Deprotection may be done with ammonium hydroxide:methylamine (1:1) at 55o C overnight if other bases are compatible.
Storage: Refrigerated storage, maximum of 2-8°C, dry
Stability in Solution: 3-5 days

minor 2’-Ome-rnaphosphoramidites

To aid in the evaluation of the structures of 2’-OMe-RNAcomplexes, we offer the CE phosphoramidites listed below. 2’-OMe-T is useful intriplex studies while the 2-aminopurine derivative may be tested in ribozymestudies. By supporting an additional hydrogen bond, 2,6-diaminopurine(2-amino-adenosine) binds more strongly with uridine than does adenosine.Oligonucleotides containing 2’-OMe-5-Me-C and 2’-OMe-I would be of interest toresearchers involved in triplex and antisense studies using 2’-OMe-RNA. The usesof 2’-OMe-5-bromo-U phosphoramidite range from crystallographic studies due tothe heavy atom to cross-linking because of its photolability.5-Fluoro-pyrimidine nucleosides have been useful as therapeutic agents and theireffect on the structure and activity of oligonucleotides may be examined usingthe 2’-OMe-RNA derivatives. The 2,4,6-trimethylphenyl (TMP) protected 2’-OMe-Uderivative is a convertible nucleoside and reaction with ammonia leads to the5-fluoro-dC analogue. 2’-OMe-3-deaza-5-aza-C (Reverse C) derivative has thepotential to mimic in oligonucleotides 5-azacytidine, a DNA methylase inhibitor.Its ability to bind as a C will likely be diminished.ABI-style vials aresupplied unless otherwise requested (see note box).

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

2"-OMe-2,6-Diaminopurine-CE Phosphoramidite

2"-OMe-2,6-Diaminopurine-CE Phosphoramidite

Glen Research

MSDS

Glen Report 6.2

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

2"-OMe-2,6-Diaminopurine-CE Phosphoramidite

2"-OMe-2,6-Diaminopurine-CE Phosphoramidite

Glen Research

DILUTION/COUPLING DATA

The table below shows pack size data and, for solutions, dilutions and approximate couplings based on normal priming procedures.

ABI 392/394
Cat.No.PackSizeGrams/Pack0.1M Dil.(mL)LV40LV20040nm0.2µm1µm10µm
Approximate Number of Additions
10-3124-020.25grams.25grams2.717746.228.882115.43.85
10-3124-90100µmoles.092grams120127.55.4541
10-3124-9550µmoles.046grams.53.3321.25.91.67.17
Expedite
Cat.No.PackSizeGrams/PackDilution(mL)Molarity50nm0.2µm1µm15µm
Approximate Number of Additions
10-3124-020.25grams.25grams4.04.0774.446.533.824.65
10-3124-90100µmoles.092grams1.5.0723.614.7510.731.48
10-3124-9550µmoles.046grams.75.078.65.383.91.54
Beckman
Cat.No.PackSizeGrams/PackDilution(mL)Molarity30nm200nm1000nm
Approximate Number of Additions
10-3124-020.25grams.25grams4.04.077647.534.55
10-3124-90100µmoles.092grams1.5.0725.215.7511.45
10-3124-9550µmoles.046grams.75.0710.26.384.64

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

品牌介绍
Athens Research & Technology—供应多款蛋白、酶制品 Athens Research & Technology是成立于2010年的新兴生物高科技制品公司,该公司拥有BSL-2实验室及超过11000平方英尺的cGMP生产厂房,并且通过ISO 9001:2008认证。Athens公司致力于纯化分离高纯度,高活性的人类蛋白质及研发多克隆抗血清产品。提供包括高纯度及活性的丝氨酸蛋白酶,蛋白酶抑制剂,中性粒细胞酶,载脂蛋白,脂蛋白,血小板蛋白,转铁蛋白,免疫球蛋白等等。公司产品适用于炎症,冠状动脉疾病,自身免疫性疾病,癌症,阿尔茨海默氏病等众多研究领域,已被世界*制药公司及诊断试剂公司用于体外诊断试剂盒/免疫检测试剂盒、药物筛选、细胞培养液(包括干细胞)等产品研发。除了人类蛋白质,我们还从动物血清和组织中分离多种蛋白质及酶类。此外,Athens Research and Technology还提供特殊试剂/蛋白定制服务,以满足研究人员的不同需求。