Aptamers: Catalogue Aptamers

Datasheet

ATW0002 Collagen Aptamer to Human Protein Target

Collagen is a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of vertebrates. It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content. The fibroblast is the most common cell which creates collagen.

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and human placental collagen protein, [Sigma Cat #C7774] as a target and 20 mM Tris, 100 mM NaCl, 0.005% Tween20, in nuclease free water, pH 7.4. Let us know if you have any questions about its development or potential uses.

Target: Collagen

Target Species: human

Target Type: protein

Affinity Constant (Kd): 42.9 nM

Default 3" Linker (Spacer) is 10T. Please submit a custom quote request for other options.

Please choose your modification and add as an extra catalogue number:ATWUNMOD - UnmodifiedATWAMINE - Amine modificationATWBIOTIN - Biotin modificationATWTHIOL - Thiol modification (extra charge)ATWFLUOR - Fluor (all) modification (extra charge)

Custom aptamers can be developed; please contact us for details.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

Antibody Equivalent Units (AEU). There is a large molecular weight difference in antibodies (typically 150,000 Da) and Base Pair’s aptamers (~14,000 Da). We provide our aptamers in terms of moles, where the aptamer moles in 1 AEU is equal to antibody moles in the typical 100 microgram shipment from a leading antibody vendor. Therefore our standard 2.5 AEU (25ug) or 5 AEU (50ug) delivery is 2.5 and 5 times the equivalent moles of a standard antibody delivery of 100 microgram respectively.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200