Aptamers: Catalogue Aptamers

Epirubicin is an anthracycline drug used for chemotherapy. It can be used in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. It is marketed by Pfizer under the trade name Ellence in the US and Pharmorubicin or Epirubicin Ebewe elsewhere.

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and epirubicin as a target and 20 mM Tris, 100 mM NaCl, 0.005% Tween20 in nuclease free water, pH 7.4. Let us know if you have any questions about its development or potential uses.

DataSheet

Please choose your modification and add as an extra catalogue number:ATWUNMOD - UnmodifiedATWAMINE - Amine modificationATWBIOTIN - Biotin modificationATWTHIOL - Thiol modification (extra charge)ATWFLUOR - Fluor (all) modification (extra charge)

Target: Epirubicin

Target Species: N/A

Target Type: small molecule

Affinity Constant (Kd): 711 nM

Default 3" Linker (Spacer) is 10T. Please submit a custom quote request for other options.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

Antibody Equivalent Units (AEU). There is a large molecular weight difference in antibodies (typically 150,000 Da) and Base Pair’s aptamers (~14,000 Da).We provide our aptamers in terms of moles, where the aptamer moles in 1 AEU is equal to antibody moles in the typical 100 microgram shipment from a leading antibody vendor. Therefore our standard 2.5 AEU (25ug) or 5 AEU (50ug) delivery is 2.5 and 5 times the equivalent moles of a standard antibody delivery of 100 microgram respectively

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

• Binding Analytics of an Aptamer to Small Molecule