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商品详细Athens Research/Cambio - Excellence in Molecular Biology/50umole/10-1585-95

Athens Research/Cambio - Excellence in Molecular Biology/50umole/10-1585-95

商品编号： 10-1585-95

品牌： Athens Research & Technology

市场价： ¥0.00

美元价： 0.00

产地：美国(厂家直采)

公司：

产品分类：多肽合成

公司分类： peptide

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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Oligo Synthesis : CEPs

Prices quoted are for single packs only. For multiples of the same product please request a quote. Some of Glen"sproductsarehazardousandmay be subject to additional shipping charges. Full product information is available onGlen Research"s website.

Pac-2-Amino-dA-CE Phosphoramidite

Glen Research

Catalogue No.	Description	Pack Size	Price	Qty	Change to: €
10-1585-02	Pac-2-Amino-dA-CE Phosphoramidite	0.25g	£200.00£190.00Offer until : 31-Mar-2021Offer Code : GLEN55% off all Glen productsView Offer	Quantity	Add to Order
10-1585-90	Pac-2-Amino-dA-CE Phosphoramidite	100umole	£100.00£95.00Offer until : 31-Mar-2021Offer Code : GLEN55% off all Glen productsView Offer	Quantity	Add to Order
10-1585-95	Pac-2-Amino-dA-CE Phosphoramidite	50umole	£56.00£53.20Offer until : 31-Mar-2021Offer Code : GLEN55% off all Glen productsView Offer	Quantity	Add to Order

Pac-2-Amino-dA-CE Phosphoramidite

Glen Research

Pac-2-Amino-dA-CE Phosphoramidite

5"-Dimethoxytrityl-N2-phenoxyacetyl-N6-di-n-butylaminomethylidene-2,6-diamino-2"-deoxypurine riboside-3"-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

Formula: C₅₇H₇₂N₉O₈P

M.W.: 1042.21

F.W.: 328.22

The simplest approach to the design of high affinity primers and probes is to substitute A sites with 2-amino-A, since the 2-amino-A-T base pair is equivalent in strength to the G-T base pair. 2-Amino-A also destabilizes A-G wobble mismatches, thus increasing specificity. In 1998, we introduced a 2-amino-dA monomer which exhibits fast and effective deprotection in ammonium hydroxide and it is stabilized to depurination during synthesis. We now recommend the use of 0.5 M CSO in anhydrous acetonitrile (40-4632-xx) for best results with multiple additions of 2-amino-dA. This is because the bis formamidine protected 2-amino-dA leads to significant strand scission when standard iodine oxidation is used during synthesis. For this reason, we have also added Pac-2-Amino-dA, a monomer with optimized protection to meet the following criteria: stable during oligonucleotide synthesis, oxidation, and detritylation; labile towards common deprotection conditions (NH3, AMA, MeNH2); and the nucleobase protecting groups are cleaved under fairly mild conditions.

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

Pac-2-Amino-dA-CE Phosphoramidite

Glen Research

Glen Report 27.2: New Product - Pac-2"-Amino-dA

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

Pac-2-Amino-dA-CE Phosphoramidite

Glen Research

Diluent: Anhydrous Acetonitrile

Coupling: No changes needed from standard method recommended by synthesizer manufacturer.

Deprotection: 30% Ammonium Hydroxide for 4 hours at 65 °C or 8-17 hours at 55 °C. Compatible with 30% Ammonium Hydroxide/40% Methylamine 1:1 (AMA) for 20 minutes at 65 °C.

Storage: Storage: Refrigerated storage, maximum of 2-8°C, dry

Stability in Solution: 1-2 days

If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200

品牌介绍

Athens Research & Technology—供应多款蛋白、酶制品 Athens Research & Technology是成立于2010年的新兴生物高科技制品公司，该公司拥有BSL-2实验室及超过11000平方英尺的cGMP生产厂房，并且通过ISO 9001：2008认证。Athens公司致力于纯化分离高纯度，高活性的人类蛋白质及研发多克隆抗血清产品。提供包括高纯度及活性的丝氨酸蛋白酶，蛋白酶抑制剂，中性粒细胞酶，载脂蛋白，脂蛋白，血小板蛋白，转铁蛋白，免疫球蛋白等等。公司产品适用于炎症，冠状动脉疾病，自身免疫性疾病，癌症，阿尔茨海默氏病等众多研究领域，已被世界*制药公司及诊断试剂公司用于体外诊断试剂盒/免疫检测试剂盒、药物筛选、细胞培养液（包括干细胞）等产品研发。除了人类蛋白质，我们还从动物血清和组织中分离多种蛋白质及酶类。此外，Athens Research and Technology还提供特殊试剂/蛋白定制服务，以满足研究人员的不同需求。

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