Oligo Synthesis : CEPs
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N6-Me-dA-CE Phosphoramidite
N6-Me-dA-CE Phosphoramidite
Glen Research
| Catalogue No. | Description | Pack Size | Price | Qty |
|
|---|---|---|---|---|---|
| 10-1003-02 | N6-Me-dA-CE Phosphoramidite | 0.25g | £396.00£376.20Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
| 10-1003-90 | N6-Me-dA-CE Phosphoramidite | 100µmoles | £130.00£123.50Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
Related products
N6-Me-dA-CE Phosphoramidite
N6-Me-dA-CE Phosphoramidite
Glen Research
| N6-Me-dA-CE Phosphoramidite |
Catalog Number: 10-1003-xx
Description: N6-Me-dA-CE Phosphoramidite
| 5"-Dimethoxytrityl-N6-methyl-2"-deoxyAdenosine, 3"-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | ||
| Formula: C41H50N7O6P | M.W.: 767.86 | F.W.: 327.24 |
Diluent: Anhydrous Acetonitrile |
| Coupling: No changes needed from standard method recommended by synthesizer manufacturer. |
| Deprotection: No changes needed from standard method recommended by synthesizer manufacturer. |
| Storage: Refrigerated storage, maximum of 2-8°C, dry |
| Stability in Solution: Similar to dA,C,G,T-CE Phosphoramidites |
MUTAGENESIS
Cellular polynucleotides are alkylated by endogenous components, such as S-adenosylmethionine, or after reacting with two general classes of environmental and laboratory chemicals. SN1 chemical agents include alkylnitrosourea and N-alkyl-N-nitro-N-nitrosoguanidine that react with the N7 position of guanine, N3 of adenine, O6 of guanine, O2 or O4 of pyrimidines, and the non-phosphodiester oxygen atoms of the phosphate backbone. In contrast, SN2 chemical agents such as methyl methanesulfonate and dimethyl sulfate react primarily with the N1 position of adenine (1-Methyl-2’-deoxyadenosine) and N3 of cytosine. To avoid chain branching during synthesis when using DCI as activator, N6-Me-dA is offered with acetyl protection.
If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
N6-Me-dA-CE Phosphoramidite
N6-Me-dA-CE Phosphoramidite
Glen Research
Material Safety Data Sheet
If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
N6-Me-dA-CE Phosphoramidite
N6-Me-dA-CE Phosphoramidite
Glen Research
EXTINCTION DATA
| Item | Nucleoside | λMax-1 | Emax-1 | λMax-2 | Emax-2 | E260 |
| (nm) | (ml/µmole) | nm | (ml/µmole) | (ml/µmole) | ||
| 10-1003 | N6-Me-dA | 266 | 16.9 | 15.2 |
DILUTION/COUPLING DATA
The table below shows pack size data and, for solutions, dilutions and approximate couplings based on normal priming procedures. Please link formore detailed usage informationwith the various synthesizers.
| ABI 392/394 | |||||||||
| Cat.No. | PackSize | Grams/Pack | 0.1M Dil.(mL) | LV40 | LV200 | 40nm | 0.2µm | 1µm | 10µm |
| Approximate Number of Additions | |||||||||
| 10-1003-02 | 0.25grams | .25grams | 3.26 | 95.33 | 57.2 | 35.75 | 26 | 19.07 | 4.77 |
| 10-1003-90 | 100µmoles | .077grams | 1 | 20 | 12 | 7.5 | 5.45 | 4 | 1 |
| Expedite | |||||||||
| Cat.No. | PackSize | Grams/Pack | Dilution(mL) | Molarity | 50nm | 0.2µm | 1µm | 15µm | |
| Approximate Number of Additions | |||||||||
| 10-1003-02 | 0.25grams | .25grams | 4.86 | .07 | 90.8 | 56.75 | 41.27 | 5.68 | |
| 10-1003-90 | 100µmoles | .077grams | 1.5 | .07 | 23.6 | 14.75 | 10.73 | 1.48 | |
| Beckman | |||||||||
| Cat.No. | PackSize | Grams/Pack | Dilution(mL) | Molarity | 30nm | 200nm | 1000nm | ||
| Approximate Number of Additions | |||||||||
| 10-1003-02 | 0.25grams | .25grams | 4.86 | .07 | 92.4 | 57.75 | 42 | ||
| 10-1003-90 | 100µmoles | .077grams | 1.5 | .07 | 25.2 | 15.75 | 11.45 | ||
If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
