Oligo Synthesis : CEPs
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dW-CE Phosphoramidite
dW-CE Phosphoramidite3-Methyl-2-pivaloyloxy-5-[2"-deoxy-3"-O-(2-cyanoethyl-N,N-diisopropylamino)-phosphino-5"-O-(dimethoxytrityl)-beta-D-ribofuranos-1"-yl]-6-(triisopropylsilylethynyl)-pyridine
Glen Research
| Catalogue No. | Description | Pack Size | Price | Qty |
|
|---|---|---|---|---|---|
| 10-1527-02 | dW-CE Phosphoramidite | 250 mg | £1,400.00£1,330.00Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
| 10-1527-90 | dW-CE Phosphoramidite | 100 umole | £560.00£532.00Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
| 10-1527-95 | dW-CE Phosphoramidite | 50 umole | £280.00£266.00Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
Related products
dW-CE Phosphoramidite
dW-CE Phosphoramidite3-Methyl-2-pivaloyloxy-5-[2"-deoxy-3"-O-(2-cyanoethyl-N,N-diisopropylamino)-phosphino-5"-O-(dimethoxytrityl)-beta-D-ribofuranos-1"-yl]-6-(triisopropylsilylethynyl)-pyridine
Glen Research
dW is a C-nucleoside that acts as a strong adenine base paring analog. In addition to the typical two hydrogen bonds found between T and A, dW can also interact with A via van der Waals forces. The result is a dW–A interaction that approaches the strength of a C–G base pair while also exhibiting enhanced base-pairing fidelity. dW can be used in place of T as a single substitution or a complete replacement for oligonucleotide hybridization applications.Please seeGlen Report article 31.21 andGlen Report article31.22for more details.
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dW-CE Phosphoramidite
dW-CE Phosphoramidite3-Methyl-2-pivaloyloxy-5-[2"-deoxy-3"-O-(2-cyanoethyl-N,N-diisopropylamino)-phosphino-5"-O-(dimethoxytrityl)-beta-D-ribofuranos-1"-yl]-6-(triisopropylsilylethynyl)-pyridine
Glen Research
If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
dW-CE Phosphoramidite
dW-CE Phosphoramidite3-Methyl-2-pivaloyloxy-5-[2"-deoxy-3"-O-(2-cyanoethyl-N,N-diisopropylamino)-phosphino-5"-O-(dimethoxytrityl)-beta-D-ribofuranos-1"-yl]-6-(triisopropylsilylethynyl)-pyridine
Glen Research
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- R. Kierzek; M.E. Burkard; D.H. Turner, Biochemistry, 1999, 38, 14214-14223.
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- M. Minuth; C. Richert, Angew. Chem. Int. Ed., 2013, 52, 10874-10877.
- T.J. Walter; C. Richert, Nucleic Acids Res., 2018, 46, 8069-8078.
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If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
dW-CE Phosphoramidite
dW-CE Phosphoramidite3-Methyl-2-pivaloyloxy-5-[2"-deoxy-3"-O-(2-cyanoethyl-N,N-diisopropylamino)-phosphino-5"-O-(dimethoxytrityl)-beta-D-ribofuranos-1"-yl]-6-(triisopropylsilylethynyl)-pyridine
Glen Research
Product Specifications
Formula:C57H78N3O8PSi
M.W.:992.30
F.W.:311.23
If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
dW-CE Phosphoramidite
dW-CE Phosphoramidite3-Methyl-2-pivaloyloxy-5-[2"-deoxy-3"-O-(2-cyanoethyl-N,N-diisopropylamino)-phosphino-5"-O-(dimethoxytrityl)-beta-D-ribofuranos-1"-yl]-6-(triisopropylsilylethynyl)-pyridine
Glen Research
- Coupling: A 15 minute coupling time is recommended. Deblocking should be carried out with 3% dichloroacetic acid in dichloromethane.Deprotection: Deprotection must be carried out in the absence of heat.
- Otherwise, all standard conditions should be compatible. Typical conditions would be ammonium hydroxide or ammonium hydroxide/aqueous methylamine 1:1 at room temperature.
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