PACKAGEDAS1MGONLY

MW:Hp1-1:86,000;Hp2-1:200,000;Hp2-2:400,000
ExtinctionCoefficient:1.20

Salt-freelyophilizedsolid.Packagedandsoldin1mgaliquots.

Storage:-20°C

BuyPurifiedNativeHumanHaptoglobin,HumanPlasma.
Price$45.00/mg.BulkQtyAvailable.

Anacute-phaseplasmaproteinfoundinhumanplasmaat100-300mgper100ml.Bindshemoglobin,thuspreventinglossofironthroughthekidneys.Humansarepolymorphicforhaptoglobin,withthreemajorphenotypes:Hp1-1,Hp2-1,andHp2-2.Whilethephenotypicdistributioncanvarygreatlybetweenethnicitiesandgeographiclocation,theHp2-1phenotypeisthemostprevalentphenotypeinhumans.PlasmaconcentrationsofhaptoglobinarehighestinindividualswithHp1-1,intermediateinHp2-1individuals,andlowestinHp2-2individuals.Hp1-1isthemosteffectiveatbindinghemoglobin,andHp2-2istheleasteffective.Thisfunctionaldifferencemaybeassociatedwiththefrequencyandseverityofepilepsyattacks,asresearchershavefoundacorrelationbetweenrecurringseizuresandtheHp2-2phenotype.

Ref:
Smithies,Oetal.1955.Biochem.J.61,629.
Sadrzadeh,S.M.H.etal.2004.Clin.Chem.50,1095.

Purity:>=95%bySDS-PAGE

ProductCitation:
Shimazaki,Youji,andMadokaMichhiro."Analysisoftrypsininhibitionactivityinhumanplasmaproteinsafterseparationbynon-denaturingtwo-dimensionalelectrophoresis." ClinicaChimicaActa (2013).

Gunasena,DilaniN.,andZiadElRassi."Hydrophilicdiolmonolithforthepreparationofimmuno‐sorbentsatreducednonspecificinteractions."Journalofseparationscience 34.16‐17(2011):2097-2105.

PreparedfromplasmashowntobenonreactiveforHBsAg,anti-HCV,anti-HBc,andnegativeforanti-HIV1&2byFDAapprovedtests.

AthensResearch&TechnologyproductsarelaboratoryreagentsandarenottobeadmiNISTeredtohumansorusedforanydrugpurpose.Forresearchuseonly.