Synonym:AGP,Orosomucoid

MW:~45,000DaunderReducingandNon-ReducingConditionsbySDS-PAGE
ExtinctionCoefficient:0.89(0.1%solution,1cmpathlength)

Salt-freelyophilizedsolid

Storage:-20°C

BuyAlpha1AcidGlycoproteinA1AGP,AGP,OMDpurifiedfromHumanplasma,directfromthemanufacturer.($30.00/1mg)

Foundinhumanplasmainconcentrationsof55-140mgper100ml.Classicalstandardglycoproteinforstudiesonthestructureoftheoligosaccharideunits.Carbohydratecontentis40%.ItsBIOLOGicalsignificanceisunknownalthoughitcanbindprogesterone15timesasstronglyasalbumin.Sialic-acid-deficientalpha-1-AGhasanaffinityforvitaminB-12.Clinically,alpha1acidglycoproteinisanacute-phasereactantthattogetherwithhaptoglobinisanindicatorofacuteinflammation.Thealpha1acidglycoprotein:haptoglobinratioisusefulinstudiesofbonemarrowdisorders,hemolyticprocessesandmetastases.

Purity:>=95%bySDS-PAGE

Ref:Schmid,K.etal.1973.Biochemistry.12,2711;Putnam,F.W.1984.ThePlasmaProteins.(Putnam,F.W.,ed.)2ndEd.Vol.IV,5.

Citations:
Brown,L.J.,etal."Miniaturizedultrahighfieldasymmetricwaveformionmobilityspectrometrycombinedwithmassspectrometryforpeptideanalysis." Analyticalchemistry 82.23(2010):9827-9834.

PreparedfromplasmashowntobenonreactiveforHBsAg,anti-HBc,andnegativeforanti-HIV1&2bycurrentFDAtestingstandards.

AthensResearch&TechnologyproductsarelaboratoryreagentsandarenottobeadmiNISTeredtohumansorusedforanydrugpurpose.
Forresearchuseorforuseinfurthermanufacturing.