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Athens Research & Technology/Transferrin (HOLO), Human Plasma/16-16-032001/100 mg
MW:80,000
Lyophilizedfrom20mMNaPhosphate,pH7.4,and150mMNaCl
Storage:-20°C
BuyPurifiedNativeHumanTransferrin(HOLO),HumanPlasma.
Price$45.00/100mg.BulkQtyAvailable.
Transferrinisamonomericglycoproteinfoundinplasmaatanaverageconcentrationof250mg/100ml.Thespecificiron-bindingproteininplasma,ithasaroleinthetransportationanddistributionofironamongthebodyorgans,inironmetabolismandpreventionofironlossviathekidneys.StoredinbonemarrowasTf-boundiron,italsopossessesbacteriostaticandfungistaticactivity.Clinically,decreasesintransferrinareobservedincongenitaldisorders,newborns,inflammatorydiseases,hypoproteinemiasandnephroticsyndrome;increasesarefoundinpregnancy,iron-deficiencyanemias,andinoculationhepatitis.Transferrinisrequiredbyalltypesofcellsinculturesformaximalgrowth.Itis,therefore,animportanttransportfactorusedindefinedculturemedia.
Purity:>=95%bySDS-PAGE
IronContent:>=1100ugpergram
Ref:MacGillivray,R.T.A.etal.1982Proc.Natl.Acad.Sci.USA.79,2504;Rivat,C.etal.1992J.Chromatogr.576,71
2013Citations:
Enns,CarolineA.,RiffatAhmed,JiaohongWang,AkikoUeno,ChristalWorthen,HidekazuTsukamoto,andAn-ShengZhang."IncreasedIronLoADIngInducesBmp6ExpressionintheNon-ParenchymalCellsoftheLiverIndependentoftheBMP-SignalingPathway." PloSone 8,no.4(2013):e60534.
Synonym:Humantransferrin,Siderophilin
PreparedfromplasmashowntobenonreactiveforHBsAg,anti-HCV,anti-HBc,andnegativeforanti-HIV1&2byFDAapprovedtests.
AthensResearch&TechnologyproductsarelaboratoryreagentsandarenottobeadmiNISTeredtohumansorusedforanydrugpurpose.Forresearchuseonly.