MW:37,000**
**Azurocidinishighlyglycosylated,whichcausestheproteintoshowalowermolecularweightbySDS-PAGEthanthatstatedof37kDa.
ExtinctionCoefficient:0.51
Salt-freelyophilizedsolid.
Storage:-20°C
BuyPurifiedNativeHumanAzurocidin,HumanNeutrophil(CationicProtein37)
Price$115.00/100ug.BulkQtyAvailable.
Thegeneforazurocidinislocatedontheshortarmofchromosome19andisinaclusterwiththegenesforproteinase3andelastase.Allthreeproteinsareserineproteasehomologues;azurocidin,however,lacksenzymaticactivity.Theimportanceofazurocidinisitsroleasamultifunctionalinflammatorymediator.Ithasantimicrobialactivity,bindsendotoxinandischemotacticformonocytes.
Purity:>=95%bySDS-PAGE
Ref:ZimmerM,MedcalfRL,FinkTM,MattmanC,LichterP,andJenneDE.1992.Proc.Natl.Acad.Sci.USA89,8215.PereiraHA.1995.JLeukocBiol.57,805.
ProductCitation:
O"Flynn,J.,K.O.Dixon,FaberKrol,M.R.Daha,andC.vanKooten."MyeloperoxidaseDirectsProperdin-MediatedComplementActivation." JournalofInnateImmunity (2013).
PreparedfromwholebloodshowntobenonreactiveforHBsAg,anti-HCV,anti-HBc,andnegativeforanti-HIV1&2byFDAapprovedtests.
AthensResearch&TechnologyproductsarelaboratoryreagentsandarenottobeadmiNISTeredtohumansorusedforanydrugpurpose.Forresearchorfurthermanufacturinguseonly.