MW:100,000
ExtinctionCoefficient:0.4
Frozenin20mMpotassiumphosphate,pH7.0,with250mMpotassiumchloride
Storage:-70°Corlower
BuyPurifiedNativeHumanC1EsteraseInhibitor,HumanPlasma.
Price$95.00/mg.BulkQtyAvailable.
AsinglechainglycoproteinwhichinhibitsC1,C1r,C1s,plasmakallikrein,FactorsXIa.XIIa,andplasmin.Presentinplasmaat16-33mgper100ml.C1esteraseinhibitordeficiencyisarareconditionresultinginfacialswellingandaBDominalcramping.Usuallytheconditionishereditary,thoughitmayalsooccurwhentheC1EIisnon-functional.
Ref:Salvesen,G.Setal.1985.J.Biol.Chem.260,2432.
Purity:>=95%bySDS-PAGE
ProductCitations:
Lee,KyoungGeun,HaneulnariLee,JeongMiHa,YoungKyungLee,HeeJungKang,Chung‐GyuPark,andSangJoonKim."Increasedhumantumornecrosisfactor‐αlevelsinduceprocoagulantchangeinporcineendothelialcellsinvitro."Xenotransplantation 19,no.3(2012):186-195
Kang,HeeJung,HaneulnariLee,Jeong-miHa,Jae-ilLee,Jun-SeopShin,Ki-YongKim,JiYoonParketal."TheRoleoftheAlternativeComplementPathwayinEarlyGraftLossAfterIntraportalPorcineIsletXenotransplantation." Transplantation (2014)
Synonym:ComplementC1esteraseinhibitor,EsteraseinhibitorC-1
PreparedfromplasmashowntobenonreactiveforHbsAG,anti-HCV,anti-HBc,andnegativeforanti-HIV1&2byFDAapprovedtests.
AthensResearch&TechnologyproductsarelaboratoryreagentsandarenottobeadmiNISTeredtohumansorusedforanydrugpurpose.Forresearchorfurthermanufacturinguseonly.