SpecialNote:Thisproductisaliquotedinsiliconizedtubes
ThisproductmustbehandledusingsiliconizedcontainersandPipettetips.
MW:420,000
ExtinctionCoefficient:0.91
Lyophilizedfrom20mMTris-HCl,pH8.0,with600mMNaCl,2mMCaCl2,and20%sucrose
Reconstitution:Afterinitialcentrifugation,wesuggesttheadditionofde-ionizedH2Ototheoriginalvolume,followedbygentleswirlingand/orvortexingtoensureadequatehomogenization.Thisproductmayprecipitateatconcentrationsgreaterthan0.50mg/ml.
Storage:-20°C
BuyPurifiedNativeHumanThrombospondin,HumanPlatelet.
PriceUSD$95.00/25ug.Bulkqtyavailable.Samedayshipping.
Acellularadhesionprotein.ThrombospondinisacomponentofthecoagulationmechanismandisbelievedtohavepotentialasaMarkerforplateletactivationandrenalfailure.
Purity:>=95%bySDS-PAGE
ProductCitations:
Stein,JeffreyJ.,ChinenyeIwuchukwu,KristopherG.Maier,andVivianGahtan."Thrombospondin-1-inducedsmoothmusclecellchemotaxisandproliferationaredependentontransforminggrowthfactor-β2andhyaluronicacidsynthase.Molecularandcellularbiochemistry(2013):1-6.
Haredy,AhmadM.,AkitoshiNishizawa,KohsukeHonda,TomoshiOhya,HisaoOhtake,andTakeshiOmasa."ImprovedantibodyproductioninChinesehamsterovarycellsbyATF4overexpression.Cytotechnology(2013):1-10.
Green,DavidE.,Bum-YongKang,TamaraC.Murphy,andC.MichealHart."Peroxisomeproliferator-activatedreceptorgamma(PPARγ)regulatesthrombospondin-1andNox4expressioninhypoxia-inducedhumanpulmonaryarterysmoothmusclecellproliferation.Pulmonarycirculation2,no.4(2012):483
PreparedfromplateletsshowntobenonreactiveforHBsAg,anti-HCV,anti-HBc,andnegativeforanti-HIV1&2byFDAapprovedtests.
Synonym:THBS1,THBS,TSP1,TSP,Thrombospondin-1
AthensResearch&TechnologyproductsarelaboratoryreagentsandarenottobeadmiNISTeredtohumansorusedforanydrugpurpose.Forresearchorfurthermanufacturinguseonly.